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Chloramphenicol, though rarely used in modern practice, can antagonize the hematologic response to vitamin B12 in patients with megaloblastic anemia

Some patients might move from, say, weekly injections to monthly injections as maintenance, then eventually to none if possible

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Novo Nordisk signed a $2.2 billion deal with Septerna for developing and commercializing oral small-molecule medicines for treating obesity, T2D and other cardiometabolic diseases

25 Classic examples are -lactamases, which hydrolyze the -lactam ring of penicillins, cephalosporins, monobactams, and even carbapenems