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Research interest has also extended to NNMTs role in cancer metabolism and tumor microenvironment modulation, where its overexpression is associated with poor prognosis in multiple cancer types

Contraindications and Drug Interactions Absolute contraindications include Wilsons Disease or other copper metabolism disorders (risk of dangerous copper accumulation), known copper allergy or hypersensitivity (risk of severe allergic reactions), and pregnancy/breastfeeding (no safety data available for systemic use)

My doctor titrated me up gradually and held back when nausea spiked at 7.5 mg