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Given the rarity of the disease, it is important to accumulate new evidence concerning diagnostic features, prognosis, and clinical outcome

One in three women undergoing axillary lymph node dissection and radiotherapy will develop this incurable and disabling disease ( As far back as 1957 studies have shown that obesity can increase the risk of secondary lymphedema ( Glucagon-like peptide 1 receptor agonists (GLP-1RAs) were originally brought to market as treatments for diabetes, and were noted to induce weight loss ( Although weight loss has been reported to be beneficial in the treatment of lymphedema, no studies to date have examined the use of GLP-1RAs for the treatment of secondary lymphedema

Scratching causes mechanical mast cell degranulation, releasing additional histamine and creating a vicious itch-scratch cycle

Streptococcus gordonii comCDE (competence) operon modulates biofilm formation with Candida albicans

Data were subsequently imported into FlowJo software (BD) for downstream analysis (Supplementary Fig