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doi: 10.3389/fcvm.2021.723996 38 AllardMFSchnekessBOHenningSLEnglishDRLopaschukGD

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The findings deliver early evidence that semaglutide may offer a dual benefit, targeting obesity and key reproductive challenges associated with the condition, including irregular menstruation and impaired fertility. Clare Thompson, MBBS, BSc, nMRCGP Separately, a review of five randomized controlled trials presented at ENDO 2026 found that GLP-1 drugs, such as semaglutide and liraglutide, do not appear to harm male fertility and may even improve testosterone levels and sperm quality in some men with obesity

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Read the timeline above as a description of aggregate trial behaviour, not as a schedule of results any individual should expect