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This gradual dose escalation is designed to minimize common adverse effects, particularly gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation

Wait 3 months after the last dose of any oral medications taken to prevent HIV infection [also known as pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP)]- Truvada (emtricitabine and Tenofovir disoproxil fumarate), Descovy (emtricitabine and tenofovir alafenamide), Tivicay (dolutegravir) and Isentress (raltegravir) are oral medications given for exposure to HIV

Any changes to antidepressant therapy should be made cautiously, with attention to mental health stability

30 January 2026

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