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While oral semaglutide has been available for diabetes (as Rybelsus), this approval makes Wegovy the first GLP-1 pill indicated for weight loss
Chen W, Fan D, Meng L, Miao Y, Yang S, Weng Y, He H, Tang X
Off-label use for low-BMI cosmetic weight loss is not supported by the evidence, exposes the patient to real risks (including rapid muscle loss and rebound after discontinuation), and typically isn't covered by insurance
doi: 10.1016/j.cell.2021.07.021 131 SulkshanePRamJThakurAReisNKleifeldOGlickmanMH
it supports cellular functions that may be relevant to exercise, hydration, cardiovascular support, and recovery-oriented formulas
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