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Effect of saffron supplementation on oxidative stress parameters: a systematic review and meta-analysis of randomized placebo-controlled trials

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This leads to a reduction in calorie intake and, consequently, weight loss

Endocrinology 145 : 26872695 Dakin CL et al

Some of its been in mice or rats, but they sort of have, you know, many have gone in and put together and extrapolated, well, if this is the mechanism of action and this is how it works, and we know these receptors are present in humans, then it would seem, you know, You know, appropriate to attempt to see if this would be helpful for this