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Prescribers or members often enter an incomplete dose (e.g., missing mg, concentration, or frequency) or fail to clearly indicate where treatment will be administered (Home vs MD Office vs hospital) and the facility details when not at home

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Autoantibodies and interferon- present in SLE sera enhance binding of the transcriptional repressor CREM to Gpx4 promoter, which leads to suppressed expression of GPX4 and subsequent elevation of lipid-ROS

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Single agent growth-inhibitory effects have been reported in breast, colon, and meningioma tumor xenografts, which suggests that GHR antagonism as a monotherapy may have efficacy in some tumor types