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Senescence is a key form of programmed cell death associated with many types of stress, such as telomere dysfunction, DNA damage, and oxidative damage

The most common cause is trisomy 21

Under moderate oxidative stress there are moderate increases on blood and cytosolic GSH and blood cysteine, while cytosolic cysteine and the [GSH]/[GSSG] ratio decline

In fact, less than 20 % of vitamin C that we consume whether through food or conventional supplements is bio-available for uptake by the cells and that is where it must reach

fabricated an intelligent nanocatalytic material consisting of copper-doped calcium phosphate (CuCaP) NPs, PEG-modified glucose oxidase (GOx), and the chemotherapeutic drug doxorubicin (DOX) PGC-DOX for efficient cancer therapy ( 2+ , and DOX will be released in response to acidic environments