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Key features Sensitive and easy-to-use colorimetric SEAP bioassay Convenient readout using QUANTI-Blue Solution Strong response to GLP-1R agonists Suitable for kinetic studies (no cell lysis required) Stability guaranteed for 20 passages Applications Therapeutic development Drug screening Release assay Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced primarily by intestinal L-cells in response to rising glucose concentrations

Whether one or more of these steroid-peptide hormone conjugates will enter clinical development remains uncertain

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Conrad M, Pratt DA

doi: 10.1021/acs.jmedchem.5b00726, 88 le RouxC