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Can Med Assoc J (1980) 122:100713
There are two distinct versions: CJC1295 with DAC Drug Affinity Complex extends the half-life to ~8 days, allowing weekly injections , but lacks pulsatility CJC1295 without DAC Shorter half-life (~30 minutes), ideal for physiological GH pulses , and preferred in performance enhancement settings For athletic performance and recovery, CJC1295 without DAC is most often chosen due to its compatibility with GHRP2 , MK677 , and BPC157
In a study titled Testosterone and Secondary Hypertension: New Pieces to the Puzzle published in the National Library of Medicine, it states that: genetic background might determine the pro-hypertensive effects of testosterone . They also state that one could hypothesize that cells derived from animals (or humans) with a genetic predisposition to arterial hypertension will respond to a greater degree to testosterone, showing greater increases in reactive oxygen species production and insufficient induction of protective NADPH oxidase subunit Nox4, resulting in an overall greater oxidative stress burden . So, men with hypogonadism will have a greater response to testosterone than men with higher testosterone levels who take exogenous androgens
