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Your GP or specialist will conduct a thorough assessment before prescribing any weight management medication, including: Calculation of BMI and waist circumference Cardiovascular risk assessment Review of comorbidities (diabetes, hypertension, dyslipidaemia) Evaluation of previous weight loss attempts Discussion of realistic goals and expectations Healthcare professionals strongly advise against obtaining medications from unlicensed sources or combining treatments without medical supervision

During much of evolutionary history, when food scarcity and caloric deprivation was a major evolutionary pressure, mechanisms evolved to minimize muscle size and thus decrease non-essential energy expenditure 42,44,55

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They reviewed more than 600 research articles and found that no one diet works for everyone, but following a few guidelines can help people to manage the condition