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Difference Between 503A And 503B Compounding Pharmacy: The 503A and 503B compounding pharmacies differ from each other in several ways from their primary purpose to various other major factors which are as follows: 503A Vs 503B Compounding Pharmacies: The two categories of compounding pharmacy, 503A and 503B are compared on various categories below: Primary Function: The primary function of 503A pharmacy is to provide customized compound medications for individual patients while 503B pharmacy aims for bulk manufacturing of compound medications for healthcare facilities