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GLP-1 (glucagon-like peptide1) is a hormone made in the gut (and to some extent in the brain) that helps with: stimulating insulin secretion when glucose is high

Acetyl l-carnitine arginate generally increases the neurotransmitter content of brain cells and helps maintain both their optimal morphology (size and shape) and their proper state of differentiation (specialization)

However, the majority of GLS inhibitors exhibit poor solubility, inadequate selectivity, and limited bioavailability, among other inherent limitations

Ethics declarations Competing interests Through M.H.H.K., the VU University Medical Center has received research grants from AstraZeneca, Boehringer Ingelheim, Novo Nordisk and Sanofi