Medicina (Kaunas, Lithuania) 2022;58:224 151
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Mice prone to atherosclerosis exhibited higher circulating TMAO levels, while those resistant to atherosclerosis showed lower levels [153]
Li Cheng, Sinopharm General Dongfeng Hospital, Hubei University of Medicine, 16 Daling Road, Shiyan, Hubei, 442000, Peoples Republic of China, Email [email protected]
HbA1c lowering effect The results of the clinical trials demonstrated significantly greater reductions in A1C with liraglutide compared to exenatide, and both GLP-1 receptor agonists caused greater reductions than those observed with sitagliptin [7] Data regarding these four agents from published head-to-head studies suggest that Liraglutide may have the largest A1C lowering capability, followed by dulaglutide, exenatide once weekly and then exenatide twice daily ( Figure 5 ) [8-10] GLP-1 RA are associated with an A1c reduction of 0.5-1.5% which is greater than 0.5-1% from DPP4 inhibitors the in head to head Duration clinical trials [11]
