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Curcumin may upregulate glutathione synthesis enzymes through activation of the Nrf2 antioxidant response element pathway (Balogun et al., 2003)

According to our study, low levels of vitamin B12 were not found to significantly predict EDS, which is consistent with prior studies including the NHANES study (n = 2459) [23] and also with studies that focused on elderly patients with chronic kidney disease (n = 367) [45] and elderly patients with or without dementia (n = 800) [46]

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