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In addition, intracellular scaffold proteins interface with the actin cytoskeleton, linking transmembrane tight junction proteins to the cytoskeleton and subsequently acting as a molecular target for tight junction dysregulation in various pathways, including the Zot and zonulin pathways, which both involve the dysregulation of tight junction proteins to induce alterations in intestinal permeability (7, 1115)

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It also may explain why KPV appears to have a favorable safety profile compared to more aggressive immunosuppressive approaches

Oxidative stress parameters after combined fluoxetine and acetylsalicylic acid therapy in depressive patients

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