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Privilege architecture failures (analysts with administrator rights, uncontrolled deletion permissions, ability to alter timestamps) recurred across diverse business modelsOTC manufacturing, sterile operations, API/drug product sites, and contract labsindicating a structural conflict of interest when the data generator also controls the data system

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The study retrospectively analysed data from patients in the Mayo Clinic Health System in the U.S

A systematic rotation pattern might involve alternating between different approved anatomical areas each week (abdomen one week, thigh the next) or rotating within the same general area by moving the injection site at least 1 inch from the previous location