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The concentration of proline was similar in control and 50 mM NaCl (around 0.71 mM g 1 FW)

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The carboxyl-terminal conjugation chemistry employed in Retatrutide represents a sophisticated approach to pharmacokinetic enhancement that extends the peptide's half-life to approximately six days while maintaining full biological activity [15] [7] [8]

10.1073/pnas.1116573109 202 ThomasA