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A relevant clue: cinnamaldehydes metabolite cinnamic acid can bind to GPR109A (discussed below), which triggers a cascade somewhat analogous to GPR120s (increasing adiponectin, anti-inflammatory)

If these observations are replicated in humans, they may contribute to our understanding of the efficacy of GLP-1 medicines in reducing chronic hypertension and protecting the kidney

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What precautions should be taken before medical procedures for patients on GLP-1 medications

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