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Efficacy and safety of once-weekly semaglutide versus once-daily Sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (sustain 2): a 56-week, double-blind, phase 3a, randomised trial

Ongoing monitoring should include regular assessment of weight loss progress, OSA symptoms (daytime sleepiness, snoring, witnessed apneas), CPAP adherence data when applicable, and potential adverse effects

The brain needs sugar (glucose) for energy, just like a car needs gas

Fibrosis extends into the enteric nervous system, where ischemia and inflammation lead to neuronal loss and reactive gliosis within the myenteric plexus, impairing communication between smooth muscle and intrinsic neural circuits [12]

It is predominantly composed of basophilic cuboidal cells