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SMALL MOLECULE ORAL GLP-1 RECEPTOR AGONISTS IN DEVELOPMENT With the established beneficial clinical profile of GLP-1 receptor agonist class, considerable efforts to develop GLP-1 receptor agonists in a noninjectable formulation are garnering attention

Clinical trials conducted on Wegovy patients revealed that approximately 44 percent reported nausea, while almost 25 percent reported vomiting, both of which are common symptoms of gastroparesis

However, these side effects are also more common at the beginning of treatment and may decrease as the body adjusts to the medication

Retatrutide shows comparable or slightly superior glycemic improvements in the limited diabetic population data available

Take home message Mounjaro is the more effective medication for both weight loss and blood sugar control based on available clinical evidence