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Biomarkers for Circadian Rhythm Disruption Independent of Time of Day

Inhibition of the GPX4 activity There are some ferroptosis inducers that block the intracellular antioxidant enzyme GPX4 through endogenous pathways

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5.2 Microbial metabolites with neuroprotective roles Microbial metabolites serve as important biochemical mediators between the gut and the CNS, regulating many neuroprotective pathways that oppose neuroinflammation and neuronal vulnerability

665 The subcellular regulation of Ca 2+ relies in part on the type II inositol 1,4,5-trisphosphate receptor (ITPR2), located on the ER membrane