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A 1985 double-blind placebo-controlled trial published in European Neurology demonstrated that DSIP administration reduced sleep onset latency by an average of 14.2 minutes and increased stage 34 sleep duration by 23% compared to placebo over a 4-week treatment period

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There is compelling evidence, including low plasma levels of GSH [12, 13], and effective antioxidant therapies (both with GSH [14] and its precursor, N-acetylcysteine [14, 15]), of REDOX imbalance contributing to the pathophysiology of several brain conditions such as obsessive-compulsive disorder, schizophrenia, bipolar disorder, autism, trichotillomania, and neurodegenerative disorders (see refs

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Previous studies indicate that excessive expression of IL-1 can lead to neuronal damage and dysfunction, potentially exacerbating cerebral edema by promoting microglial activation and inflammatory responses [76, 77]

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