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GLP-1 medications increase the time food spends in your stomach, slowing gastric emptying and signaling fullness to your brain
Therefore, men on important oral meds (like certain diabetes drugs, blood thinners, etc.) should separate their dosing from PT-141 by a couple of hours and monitor those medications effectiveness
After 108 weeks, changes in UACR from baseline with lixisenatide were 1.69% [(95% CI: 11.69 to 8.30), p=0.7398] in patients with normoalbuminuria, 21.10% [(95% CI: 42.25 to 0.04), p=0.0502] in patients with microalbuminuria, and 39.18% [(95% CI: 6853 to 984), p=0.0070] in patients with macroalbuminuria
Absorption is rapid regardless of route (peak plasma levels within 3090 minutes), and theres no evidence that route of administration affects NNMT inhibition efficacy
Herskowitz: But sometimes you have to have an overlay of someone looking at it themselves
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