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Epidemiological data show that individuals in the highest IGF-1 quartile carry a modestly elevated risk for certain cancers, including colorectal, breast, and prostate [12]

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STAT proteins, particularly STAT3 and STAT5, play central roles in the expansion, activation, and immunosuppressive functions of MDSCs [89]

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Colluci and colleagues [150] used an in vitro model to suggest that carnitine supplementation in the elderly may stimulate osteoblast activity and decrease age-related bone loss

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