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doi:10.1080/14656566.2024.2314087 Gupta, A

doi: 10.1111/imm.13390 37 JungJSajjadianSMKimY

141 They remain in the body, interacting with GLP-1 receptors in various organs, which could lead to DDIs through mechanisms of action such as slowing gastric emptying, reducing fat mass and inflammation, and increasing glomerular filtration rate (GFR) and renal plasma flow, consequently altering the pharmacokinetics of the victim drug (Figure 3)

Single-cell RNA sequencing has shown age-related activation of the macrophage pyroptosis pathway, which accelerates stromal cell senescence and reproductive decline (Zhou C