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Ongoing trials are recommended to assess long-term body mass changes after discontinuing semaglutide, which is important for understanding its lasting effects on weight management

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Both dextromethorphan and bupropion are sigma-1 receptor agonists that can modulate glutamate and monoamine signaling (Fig

Semaglutide is a GLP-1 receptor agonist that has been studied for stimulating glucose-dependent insulin secretion and modulating central appetite regulation pathways