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That said, this does not establish clinical efficacy in humans, and the current human evidence picture for BPC-157 across all applications remains limited.* These statements have not been evaluated by the FDA

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(PMC) A separate metabolism-focused paper reviewing human trial history makes a similar point: early signals of weight loss were not consistently reproduced in later studies, particularly when intensive diet/exercise protocols were included

Others complain of constipation, which can be alleviated through sufficient hydration and consumption of fiber

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