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Vitamin B is essential for red blood cell formation, nerve function, and DNA synthesis

Single nucleotide polymorphism in the gene leading to an Arg 213 His amino acid substitution is relatively frequent in the Caucasian population (25.436.5%) (Glatt & Meinl, 2004)

Later, in response to yet unidentified triggers, silent autoimmunity eventually turns into a clinically apparent inflammatory disease such as RA

Sulodexide in venous disease