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Larger vials almost always offer better per-milligram value, but only if you can use them within the 28-day reconstitution window

There is a theoretical case for using both in certain patients, targeting different physiological mechanisms simultaneously, though this approach is under evaluation and not yet standard of care

If the phenytoin levels are too high, it may take days or even weeks to return to the desired range

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This is usually reserved for more severe cases of deficiency and per the discretion of your healthcare provider