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The effect on astrocytes may happen independently of Nrf2, since cofilin-1, tubulin and collapsin response mediator protein 2 (CRMP2) activity was seen to be mediated by DMF and reduced cytoskeletal remodeling (173)
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In contrast, presence is a subjective phenomenon, reflecting the users perceived involvement and emotional activation during the virtual experience (Tieri et al., 2018
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