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It performs an array of critical functions, including detoxifying drugs, protecting macromolecules from oxidative damage, and maintaining immune functions [ 1]
This interaction is enabled by the hydrophobic nature of both components in the hydrogel, including the poly(lactic acid) (PLA) core of the PEG-PLA nanoparticles and the dodecyl moieties on the HPMC-C12 polymers
Resveratrol administration after prenatal exposure to VPA in rats, resulted in prevention or reduction of autism-like social deficits, pregnant Wistar females received a single intraperitoneal dose of VPA (600 mg/kg) on gestational day 12, while resveratrol was administered subcutaneously at 3.6 mg/kg/day from gestational day 6.518.5