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- Medical News Today, accessed April 23, 2025, Weight Loss Outcomes Associated With Semaglutide Treatment for Patients With Overweight or Obesity - PMC, accessed April 23, 2025, Once-Weekly Semaglutide in Adults with Overweight or Obesity - PubMed, accessed April 23, 2025, STEP-1-Trial.pdf - Centre for Cardiovascular Innovation, accessed April 23, 2025, Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial - ResearchGate, accessed April 23, 2025, Treatment with tirzepatide in adults with pre-diabetes and obesity or overweight resulted in sustained weight loss and nearly 99% remained diabetes-free at 176 weeks - Eli Lilly Investors, accessed April 23, 2025, SURMOUNT-1 trial finds tirzepatide supports long term weight control, accessed April 23, 2025, Tirzepatide Bests Semaglutide for Weight Loss: SURMOUNT-5 Topline Results | tctmd.com, accessed April 23, 2025, Tirzepatide Versus Semaglutide on Weight Loss in Type 2 Diabetes Patients: A Systematic Review and Meta-Analysis of Direct Comparative Studies - PubMed, accessed April 23, 2025, Potent incretin-based therapy for obesity: A systematic review and meta-analysis of the efficacy of semaglutide and tirzepatide on body weight and waist circumference, and safety - PubMed, accessed April 23, 2025, Semaglutide Versus Other Glucagon-Like Peptide-1 Agonists for Weight Loss in Type 2 Diabetes Patients: A Systematic Review and Meta-Analysis - PubMed, accessed April 23, 2025, Zepbound (Tirzepatide) vs

Large portions are also problematic because gastric emptying is slowed smaller, more frequent meals work better