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This double layer of epithelium is composed of a pigmented epithelium (PE), which interfaces with the highly vascularized stromal tissue that contains fenestrated capillaries, and a non-pigmented epithelium (NPE) which interfaces with the aqueous humor [73]

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277,278 Collectively, these observations emphasize that the metabolic phenotype of CSCs is deeply context dependent and shaped by both the tumors tissue of origin and ongoing crosstalk within the TME

The NAD infusion drip was absolutely painless