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In the United States, a recent analysis of reports of perinatal exposure to GLP1RAs found a rise from less than 50 cases per 100,000 pregnancies in 2012 to over 200 cases per 100,000 pregnancies in 2020 [15] and a separate study in the US state of Maine showed that perinatal exposure to GLP1RAs rose from 0.02% in 2017 to 0.29% in 2023 [16]

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Specifically, Shih et al

Semaglutide vs Traditional Weight Loss Drugs Older weight loss medications like phentermine, orlistat, or naltrexone-bupropion produce much more modest resultstypically 5-10% weight loss compared to semaglutides 12-15%