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A history of active cancer is a major contraindication for these therapies, as growth-stimulating hormones could theoretically influence tumor growth

of Clinical Epidemiology, College of Medicine, University of the Philippines Manila, 2016 (unpublished)

NUPR1 inactivation can regulate mitochondria-related ferroptosis through mitochondrial dysfunction, decreased antioxidant capacity, and increased accumulation of endogenous iron content [84]

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[DOI] [PMC free article] [PubMed] 1156.Zhang L, et al