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In clinical studies of Huntingtons disease, treatment-emergent adverse events included somnolence and sedation, urticaria, rash and insomnia

There is some intriguing data suggesting that GIP, at least in animals, mitigates some of the adverse events that can be induced by GLP-1, says Drucker

Effect of histamine and bradykinin on lymph and tissue fluid composition in the rabbit hindlimb: evidence for two compartments in tissue fluid