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Combination with insulin requires insulin dose reduction (often significant) to prevent hypoglycemia

massiliensis were then extracted from quality-filtered reads by using blastn algorithm [38] ( e value 50% stenosis for at least one coronary vessel) were recruited as an independent cohort for validating the microbiome-based TMAO producer prediction model (the baseline characteristics of CVD validation cohort were described in Table S2)

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The N-terminal domain of the target-binding site has two residues, Glu 5 and Glu 9, that are the most highly conserved in S100 proteins (136)

The prescribed medication is not in the formulary