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The resulting crude peptide is then cleaved from the resin, deprotected, and subjected to multistep purification (chromatography, crystallization) to remove byproducts, protecting groups, and residual solvent ( [20] )

Broader Implications for Obesity Treatment These results place retatrutide ahead in the race for effective obesity treatments, showing promise not only in weight management but also in improving blood pressure and other metabolic markers. Researchers observed that most weight loss occurred in the early stages of treatment, with results stabilising over time

And its expected that it will be approved in the next some amount of time

doi:10.2337/dc23-S011 Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jdar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML, Woo V, Hansen O, Holst AG, Pettersson J, Vilsbll T

In the SURMOUNT-1 trial, tirzepatide produced average weight reductions of 15.0%, 19.5%, and 20.9% at studied doses compared with 3.1% with placebo over 72 weeks