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Tirzepatide is a dual agonist for the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors

The in vivo study showed a significant reduction in TMAO levels in C57BL/6(FMO3 +/+ ) strain WT mouse models and in TMA levels in C57BL/6 -Fmo3em1Smoc (KO) mouse models

Keywords: glucagon-like peptide-1 receptor agonist, obesity, overweight, semaglutide, sleeping habits Introduction The number of individuals with overweight and obesity has been considerably increasing worldwide