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WD increased inflammation in a sex- and region-specific manner, and GE2 reduced inflammation in the hippocampus in SD-fed rats, as well as in the amygdala of males regardless of diet Brain aging is associated with increased inflammation, however diets, such as the WD, may further affect inflammation

(5) Shayan Yaghmayee, Atefeh Sadat Moazzeni, Tannaz Jamialahmadi, Sercan Karav, Habib Yaribeygi, Prashant Kesharwani, Amirhossein Sahebkar, Neuroprotective and cognitive benefits of Semaglutide: Insights into the underlying molecular mechanisms, Neuroscience, Volume 579, 2025, Pages 187-197, ISSN 0306-4522 (6) Zheng, Z., Zong, Y., Ma, Y

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GLP-1 helps to regulate this by signaling the pancreas to release insulin, the hormone responsible for lowering blood sugar levels

DHLA is a powerful antioxidant that is produced in the body when alpha lipoic acid reduction occurs during various cellular processes