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Regulatory positions vary by jurisdiction and change over time

NLRC4: NLR Family CARD Domain Containing 4

5 Conclusion The antioxidant effects of Spirulina platensis aqueous extract (SPAE) contributed to regulating biochemical parameters, including liver enzymes and lipid profiles, in male rats subjected to dexamethasone-induced oxidative stress

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Substances produced by physiologic stress or calorie reduction (e.g., 3-carboxy-4-methyl-5-propyl-2-furan propanoic acid (CMPF), indoxyl sulfate, bilirubin and fatty acids), have been shown to reduce the cellular uptake of T4 by up to 42%, while having no effect on T4 or T3 uptake into the pituitary