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As severe (grade3) gland atrophy, scanty lacy colloid, cell desquamation, vacuolization and inflammation were significantly the highest in group III (GLP group) (75%,62.5%,50%,75%) compared to (0%) in other groups (I, II, IV) respectively, also focal adenomatous changes were significantly higher in group III (GLP group) (62.5%) compared to (0%) in groups (I, and II) and (12.5%) in group (IV) respectively ( p = 0.037414, 0.037414,0.0027, 0.0455 & 0.038867, respectively) (Table 6