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Contraindications include personal or family history of medullary thyroid carcinoma or MEN 2 syndrome, pancreatitis history, severe GI or kidney disease, pregnancy, and breastfeeding

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This is why flat-rate pricing generally represents the better value for most patients, since the standard tirzepatide dosing protocol involves gradual escalation from 2.5 mg to higher doses over several months

This could mean your TSH (Thyroid Stimulating Hormone) levels drop lower than intended, potentially pushing you towards a slightly "overactive" state