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p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells

The challenge for oral GLP-1s will not just be meeting demand from existing interest groups, but expanding awareness to the much larger population who still know very little about these treatments

Regarding the catalytically advantageous nature of Sec, studies of Cys-substituted murine GPx-1 indicate that in the context of mammalian Sec-containing GPxs, the Sec active site may have the added advantage of being less sensitive to overoxidation and inactivation in the presence of peroxides compared to Cys (309)

The underutilization of GLP-1 RAs presents an opportunity to improve outcomes in this high-risk population without increased complications

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