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It can influence pro-inflammatory molecules like interleukin-6 (IL-6) and TNF-alpha, which are linked to prolonged inflammation in injury models

A cardiovascular disease-linked gut microbial metabolite acts via adrenergic receptors

Similarly, glucoraphanin-rich broccoli (400 g/week) consumed over a 12-week period was found to significantly reduce plasma LDL-C compared to consumption of standard broccoli in two randomized, double-blind parallel studies including 130 adults aged 50 years at risk of cardiovascular disease ( Neurological and Psychiatric Disorders Preclinical evidence suggests that glucosinolates and their metabolites, particularly sulforaphane, exhibit several biological properties that may be relevant to neurological and psychiatric conditions (Wu et al., 2016

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NICE guidance (TA875) recommends semaglutide 2.4 mg for weight management through specialist weight management services, with specific BMI thresholds and typically limited to 2 years of treatment on the NHS