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The FDA-approved prescription omega-3 formulation icosapentaenoic acid ethyl ester (Vascepa, 4 g/day) reduced fasting triglycerides by 33% versus placebo in the MARINE trial (N=229) [5]

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doi: 10.1016/j.freeradbiomed.2020.12.017 219 WaltherBKarlJPBoothSLBoyavalP

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It promotes lipolysis , the breakdown of triglycerides into free fatty acids used for energy, aiding in reductions in body fat percentage (Yaspelkis & Ivy, American Journal of Physiology )