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Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription: Synergistic activation of Nrf2 by CBP

All above samples were diluted (1:1) with 20% ACN/0.1% FA, containing 100 nM of deuterated internal standards and analysed by LC-MS/MS

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In order to support this conceptual opening, the contribution presents the preliminary findings of a comparative analysis of 'functional areas' definitions based on an extensive literature review