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Too much of a good thing may cause undesirable side effects
For example, research has shown that the GLP-1 receptor agonist liraglutide can alleviate pain hypersensitivity in chronic migraine models by stimulating interleukin-10, suggesting its potential to modulate central sensitizationa crucial mechanism in chronic pain 62
This selectivity makes it ideal for research on growth hormone regulation and potential therapies
PCOS and GLP-1s: Improving Reproductive Functionality For PCOS, the human evidence on GLP-1 medications is compelling enough that they now feature in the 2023 International PCOS Guidelines, though as a conditional recommendation (1)
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